Hypervariable loci that enhance the discriminatory ability of newly proposed 15-loci and 24-loci variable-number tandem repeat typing method onMycobacterium tuberculosisstrains predominated by the Beijing family
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چکیده
منابع مشابه
VNTR9 and VNTR10, two newly-found variable-number tandem repeat loci useful in MLVA genotyping of Bordetella pertussis
Background & Aims: Bordetella pertussis, the causative agent of whooping cough, continues to infect human hosts even in those populations where infants and children are routinely vaccinated. Causes of pertussis epidemiology are not fully identified unless strains of the pathogen are characterized by molecular means. Golbally, Multi Locus Variable Number of Tandem Repeats analysis (MLVA) has pro...
متن کاملDiscriminatory Ability of Hypervariable Variable Number Tandem Repeat Loci in Population-based Analysis of Mycobacterium tuberculosis Strains, London, UK
To address conflicting results about the stability of variable number tandem repeat (VNTR) loci and their value in prospective molecular epidemiology of Mycobacterium tuberculosis, we conducted a large prospective population-based analysis of all M. tuberculosis strains in a metropolitan setting. Optimal and reproducible conditions for reliable PCR and fragment analysis, comprising enzymes, den...
متن کاملDiversity of Variable Number Tandem Repeat Loci in Shigella Species Isolated From Pediatric Patients
Multilocus variable number tandem repeat (VNTR) analysis (MLVA) is a new typing method with several advantages compared to other methods. Dissemination of Shigella is highly significant in developing countries. Whilst Shigella is becoming increasingly important as an etiologic agent of pediatric shigellosis in Iran, little is known about the genetic diversity of the local strains. Therefore, th...
متن کاملdiversity of variable number tandem repeat loci in shigella species isolated from pediatric patients
multilocus variable number tandem repeat (vntr) analysis (mlva) is a new typing method with several advantages compared to other methods. dissemination of shigella is highly significant in developing countries. whilst shigella is becoming increasingly important as an etiologic agent of pediatric shigellosis in iran, little is known about the genetic diversity of the local strains. therefore, th...
متن کاملIntrinsic polymorphism of variable number tandem repeat loci in the human genome.
In the human genome, short tandem repetitive (STR) DNA sequences often show restriction fragment length polymorphisms (RFLPs) due to variation in the number of copies of the repeat unit. For a subset of these sequences known as minisatellites or variable number tandem repeat loci (VNTR), it has been proposed that a homologous "core" sequence of 10-12 nucleotides is involved in the mechanism(s) ...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 2007
ISSN: 0378-1097,1574-6968
DOI: 10.1111/j.1574-6968.2007.00777.x